In your case,all customers would use the same ip.You might use same from domain for all customers.If you do so,all customers will have the same reputation.
If you use different from domains,then you might see different results sent to general domain names(some customers might inbox and some might junk.)
But when it comes to big ISPs like yahoo,aol,hotmail,gmail , it would not make much difference to use different mailfroms as they mostly care on the ip reputation.
Hope this helps.